Nature2026
A deep-learning framework reveals whole-body perturbations at cell level
Doris Kaltenecker et al.
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Nature · 2026
MouseMapper
Whole-body nervous & immune architecture in 3D
Whole-body nerve architecture
Whole-body reconstructions of normal (left) and obese (right) UCHL1-EGFP mice. Peripheral nerves (UCHL1-EGFP+) are shown in green, bones and organs are shown in red (propidium iodide labeled) and muscle (autofluorescence) is shown in blue.
Foundation-model deep learning segments and quantifies whole-body nervous and immune systems in cleared mice — revealing systemic remodeling in obesity and disease.
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Lab contributors
Current Ertürk Lab members linked to this project.
Doris Kaltenecker
Postdoc
Ying Chen
Ph.D. Candidate
Luciano Höher
Master Student
Mihail Todorov
Postdoc
David-Paul Minde
Staff Scientist
Louis Kümmerle
Ph.D. Candidate
Denise Jeridi
Lab Technician
Laurent Simons
Ph.D. Candidate
Farida Hellal
Co-deputy
Markus Elsner
Co-deputy
Harsharan S. Bhatia
Omics Technologies Team Leader
Ali Maximilian Ertürk
Director
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