Technology & Research · Overview
Enabling technologies for whole-body biology
Our major goal is to accelerate biomedical research by developing and combining enabling technologies. We combine biomedical research with artificial intelligence, nanotechnology, and engineering to solve major bottlenecks in research — from whole-body imaging to molecular analysis at single-cell resolution.
AI-based organ mapping
AI-based organ mapping
Using tissue clearing paired with AI deep learning algorithms we map mouse and human organs at the cellular level.
- Skull–meninges connections and drug delivery routes into the brain (Nature Neuroscience, 2019)
- Mapping the human brain using SHANEL transparency (Cell, 2020)
- Exploiting unbiased vascular analysis (Todorov…Ertürk, 2020, Nature Methods) to investigate brain pathologies including stroke and dementia
Precision medicine in cancer
Precision medicine in cancer
DeepMACT images and analyses cancer metastasis and drug targeting in whole mice at cellular resolution, combined with organoid models and AI profiling.
- DeepMACT — whole-body metastasis imaging (Cell, 2019)
- Organoid screening pipelines for treatment resistance
- Cell-level precision in cancer treatment strategies
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Projects & publications
Browse lab platforms and the peer-reviewed papers behind them.